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Annalen der klinischen und Laborforschung

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Is Topical Antifungal the Appropriate First Choice for Denture Stomatitis?

Isadora Luana Flores, Luiza Teixeira Souza and Ana Paula Neutzling Gomes

Background: Denture stomatitis (DS) is commonly diagnosed during the routine intraoral examination of prosthesis wearers. Episodes of DS relapse occur frequently.

Objective: This study aimed to investigate the therapeutic agents against DS lesions through a briefly review of the English literature on the comparison between topical and systemic protocols.

Materials and methods: A descriptive research was performed on articles published in PubMed/Medline using specific keywords following pre-established inclusion and exclusion criteria.

Results: Only two studies clinically compared topical and systemic protocols for DS treatment.

Conclusion: In vivo comparative studies on topical and systemic antifungal protocols against DS are extremely scarce. Thus, we recommend additional investigations on the drug principles, time of prescription, side effects and the best approach for choosing an antifungal drug. Finally, prosthesis care is a key factor to prevent DS lesions.