Emma Grace Oreskovic*
Comprising the refractive component of the eye, the cornea is a fundamental component of the human visual apparatus. The vitality of the structure is recognized in instances where it is functionally impaired, most commonly due to ulceration-induced scarring, infection, traumatic events, as well as autoimmune disorders. Consequently, such pathologies result in blindness. With the current global incidence of corneal blindness affecting over 10 million individuals, further research and development in this area of healthcare is crucial. Current approaches addressing corneal blindness include transplantation with cadaveric donor corneas, or, more recently, inserting the ologenTM Biocornea as a temporary patch over a corneal injury until a donor cornea is made available. Several attempts have been made to produce a viable synthetic cornea using collagen-based biomaterials, a few of which will be discussed in this review.
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