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Archive in der Krebsforschung

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Specific Accumulation of a Cell Penetrating Peptide Targeting AAC-11 in Melanoma Tumors

Ewa Kotula, Léonard Jagot-Lacoussiere, Heriberto Bruzzoni-Giovanelli and Jean-Luc Poyet

Melanoma is the most serious and potentially dangerous form of skin cancer with a rapid increase in prevalence, especially among western countries. The prognosis for patients with the more advanced form of the disease, metastatic melanoma, remains poor with survival rates ranging from 6.7% to 8% at 5 years, and a median survival of 6 to 9 months. Therefore, there is a clear unmet clinical need to identify new drugs to combat melanoma.